Anabolics // Category

Category based archive
18 Jan

Baseball aficionado Larry King says that steroids shouldn’t be a major issue when players are assigned for Hall of Fame actuation. “I’d vote in favor of (Barry) Bonds and (Roger) Clemens since I think they were Hall of Famers before (steroid) utilize,” the incredible supporter tells [email protected] Ruler includes: “I don’t know why HGH (Human Growth Hormones) is banned. It just makes you recuperate rapidly. Why isn’t headache medicine banned? On the off chance that you have a migraine, you take ibuprofen and the cerebral pain leaves.”

30 Dec

Testosterone Enanthate (delatestryl)

Testosterone is in charge of the typical development and advancement of the male sex organs and for the upkeep of the optional sexual qualities. The medication can influence the development of the prostate, testis, fundamental vesicles, penis and scrotum furthermore is essential for body development. Despite the fact that testosterone is an androgenic hormone, it does gangs anabolic properties. Its utilization has been appeared to advance protein combination and a positive nitrogen equalization in the vicinity of a rich calorie diet.

 

Testosterone likewise can bring about a mellow increment in the creation of red platelets by invigorating the amalgamation of from the kidney. This outcomes in an expansion in the red platelets and thus an expansion in the oxygen conveying limit.

At the point when testosterone is taken for delayed periods, it represses the arrival of Gonadotropins from the pituitary organ through a negative criticism system. Everywhere dosages, it can even hinder spermatogenesis.

Testosterone likewise can bring about a gentle increment in the creation of red platelets by animating the union of EPO from the kidney. This outcomes in an expansion in the red platelets and thus an increment in the oxygen conveying limit.

At the point when testosterone is taken for delayed periods, it hinders the arrival of Gonadotropins from the pituitary organ through a negative criticism system. Everywhere measurements, it can even repress spermatogenesis.

Dose

Testosterone enanthate (Delatestryl) is only slowly released after an intramuscular injection and that is why it should not be taken more than 1-2 times a month. The formulation comes as an esterified preparation of testosterone which is only meant to be administered by an intramuscular injection. The esterification of the testosterone increases the duration of action of the testosterone. The preparation comes in a colorless to mild yellow suspension of sesame oil. For medical uses, a dose of 250-500mg is used once a month.

Indications

Delatestryl is indicated in the treatment of conditions where testosterone is either deficient or absent. These conditions include:

  • primary hypogonadism- where the testes has been injured and fails to make the testosterone
  • Hypogonadism due to failure of the pituitary gland to release of Gonadotropins.
  • delayed puberty
  • In females with breast cancer, testosterone may help block the effects of estrogen and prevent further spread. It is an option instead of surgical removal of the ovaries.

In most cases of testosterone deficiency, therapy is required for a long time until the secondary sexual characteristic have been developed and the growth is adequate.

Duration

The treatment of all people with testosterone enanthate relies on upon age, sex, finding and the reaction to treatment-and the onset of unfavorable impacts. By and large, the medication is all around endured when endorsed as suggested. Delatestryl ought to dependably be infused in the butt cheek muscles and not just underneath the skin. The infusion site ought to be turned to forestall ulcer development. Another choice is to infuse the medication on the outside of the thigh. The medication ought to never be regulated intravenously.

The measurement of testosterone enanthate ought not surpass more than 400 mg for every month on the grounds that the medication has drawn out action. It is to a great degree uncommon to give this medication once like clockwork. The medication ought to dependably be examined before infusion. It is normally a dry yellow suspension which is clear. Any particulate matter or clustering shows that the item is terminated or dormant. The term of treatment changes from 4-6 months.

The drug should be stored at room temperature.

Bodybuilders

A lot of bodybuilders use Delatestryl during the off season. The drug stays in the body for a long time and it is advisable not to use it during the active sports season. The drug definitely has anabolic and androgenic properties. However, the effects of the drug are not immediate and may take at least 3-4 weeks to become evident. Many bodybuilders also use other anabolic hormones like GH/thyroxin in combination.

Because testosterone is also converted to estrogen in the fatty tissues, many bodybuilders develop breast enlargement and retain water. The dose used to increase muscle mass and strength is about 250-1000 mg/week. However, at the higher doses the drug has potent side effects and it is highly recommended that all beginners start off with the low dose.

The increase in protein mass is gradual but does occur. Because the steroid also stimulates red blood cell production, many bodybuilders also notice that they have an increased capacity to perform under intense exercise conditions. Testosterone enanthate is preferred by most bodybuilders because it is readily available and has a number of benefits. It promotes good health, increase exercise performance and leads to a positive nitrogen balance. There are reports that it also selectively decreases fat and increases muscle mass. Recent studies from the World sports agencies indicate that this particular drug can boost performance, increase lean muscle mass and still not bedetected in the urine within the first few weeks. Even when the anabolic effects are not obvious, most individuals do notice an increase in strength. Sometimes the water retention can be quite dramatic and some individuals do take a diuretic pill to remove it. To prevent the breast enlargement, testosterone enanthate is cycled with drugs like Arimidex or Tamoxifen. Most individuals take the testosterone for 4-6 weeks and then stop for a few weeks. During this wash out phase, one may use Arimidex.

Women

All testosterone analogues have the potential to cause virilizing effects when the duration of use is prolonged. In females, these virilizing signs may be deepening of voice, excessive hair growth, irregular menstrual cycles, mood alterations and clitoral enlargement. It is recommended that at the first sign of virilizing symptoms the drug should be stopped. The reason for this is that some of the virilizing signs may not be reversible even after discontinuation of the steroid.

Side effects

Like all anabolic steroids, testosterone enanthate has a few side effects. These side effects are generally mild and well tolerated. The majority of individuals do see some side effects after 3-4 months of therapy. The most common side effects include:

  • irregular menstrual cycles
  • virilizing effects
  • deepening voice
  • clitoral enlargement
  • gynecomastia
  • painful penile erections
  • hair loss, acne oily skin
  • retention of body water
  • nausea, vomiting, jaundice
  • liver cancer (rare)
  • mental changes, depression, headaches, anxiety,
  • increased serum cholesterol

While most of these side effects are reversible, the breast enlargement and some virilizing effects are not. The concomitant use of estrogens to diminish the side effects of virilization is not always helpful.

In children the use of testosterone must be strictly monitored. It can accelerate bone maturation but does not increase compensatory linear growth – which results in abnormal body distortion in anatomy- esp. the jaw and face.

Warnings

The drug should be used very cautiously in individuals with:

  • breast cancer and hypercalcemia
  • liver dysfunction
  • prostate cancer
  • heart problems

There have been isolated reports of individuals developing a dry cough, breathing difficulties after injection with testosterone enanthate. This has been linked to the oil based preparation or a contaminant in the formulation.

All individuals who use testosterone should have their liver enzymes and blood hematocrit regularly checked to ensure that they are within normal limits.

Legal

Delatestryl is classified as a class 3 drug under the controlled substance act. In the USA, it is only available with a physician’s prescription.

Detection

Testosterone enanthate has a long half life in the body. Consequently it is additionally identified in the pee long after it has been stopped. Current methods of testing can recognize testosterone or its metabolites in the pee no less than 3-4 weeks after the medication has been ceased. Infact, the testing has even gone past pee testing. In the event that exorbitant utilization of the testosterone is suspected, one can even detect hints of the testosterone in the hair 2-4 months after the medication has been abated.

However, one should know that the testing today for testosterone enanthate is not perfect. About 50% of individuals who take this steroid are missed based on the testosterone/epitestosterone ratios.

Cost

The legal testosterone enanthate is quite difficult to get hold off. The majority of bodybuilders get their testosterone from the black market. Generic testosterone formulations made in Europe and Mexico are widely available. The drug is not cheap and a vial of 250 mg can cost anywhere from $10-$20. In the last 2 decades, the increasing control of these drugs by the DEA has led to unscrupulous dealers selling fake or counterfeit products. So in the end, it is always buyer beware.

07 Dec

For the amateur, there is no particular drug labeled testosterone suspension. Testosterone is a huge molecule and insoluble in water. To make formulation of the testosterone which can be injected, the steroid is often dissolved in a number of oils.

To the lipid solubility of the steroid, one can add an array of compounds to the side of the molecule which alters it absorption and length of action. Testosterone formulations come with a variety of side chains such as proportionate, acetate, decanoate, etc. When each of these is mixed in sesame seed oil it is called a suspension.

 

Esterification of testosterone is done so as to enhance the solvency of testosterone in oil, which thus moderates the arrival of the testosterone from the site at which it enters the body.Suspensions of testosterone can not be taken in orally. There must be infused intramuscularly. From the infused site the steroid is step by step retained gradually into the circulatory system.

A few suspensions get absorbed more rapidy than others. In all cases, suspensions of testosterone don’t should be infused once a day. A large portion of them stay as a stop in the butt cheek muscles for a couple of days to a week.Testosterone or tesamone is just a slick suspension of testosterone. It has the same movement as all testosterone items. It is both an anabolic and an androgenic operators. There are numerous sorts of testosterone suspension accessible in the USA. Obviously one needs a doctor’s medicine. Testosterone suspensions are utilized to treat issue where there is an insufficiency of testosterone combination or issues with the arrival of the Gonadotropins. Testosterone is demonstrated to treat guys with:

  • infertility
  • delayed puberty
  • women with advanced breast cancer
  • promote growth in malnourished individuals

Pharmacology
Testosterone is responsible for the normal growth and development of the male sex organs and for the maintenance of the secondary sexual characteristics. The drug can affect the growth of the prostate, testis, seminal vesicles, penis and scrotum and also is important for body growth. Even though testosterone is an androgenic hormone, it does posses anabolic properties. Its use has been shown to promote protein synthesis and a positive nitrogen balance in the presence of a rich calorie diet.

Testosterone also has the ability to cause a mild increase in the production of red blood cells by stimulating the synthesis of EPO from the kidney. This results in an increase in the red blood cells and hence an increase in the oxygen carrying capacity.

When testosterone is taken for prolonged periods, it inhibits the release of Gonadotropins from the pituitary gland through a negative feedback mechanism. At large doses, it can even inhibit spermatogenesis.

Dose
All testosterone suspensions are administered as an intramuscular injection and remain in the body for up to 48-72 hours. Testosterone can be detected in the urine for a lot longer period. The esterification of the testosterone increases the duration of action of the testosterone. There are many athletes who complain that injection of testosterone suspensions into the buttock area is painful. This pain may be due to injection of large amounts of the drug or the development of an abscess. It is best to use a low volume of the drug for injection and rotate to the site to prevent abscess formation.

The recommended dose of testosterone suspension for the novice body builder is about 25 mg once a week. There are others who start off at 50-100mg/week. And yet there are others who combine the various testosterone formulations in a cocktail. The duration of testosterone treatment should be limited to 4-6 weeks to allow for the hypothalamic – pituitary axis and testes to recover.

During the washout phase of the drug, many athletes take or Nolvadex (tamoxifen) to prevent the estrogenic side effects of the testosterone.All vials should be inspected prior to the injection. During storage one may see some fine crystals which should disappear after shaking the vial. If the crystals remain, then the vial should not be used for injection.

Like all testosterone products, use of testosterone suspensions inhibits the synthesis of testosterone in the testes and affects the hypothalamic pituitary axis. For this reason, the testosterone should not be abruptly stopped but tapered off slowly.

Duration
The treatment of all individuals with testosterone suspensions depend on age, sex, diagnosis and the response to treatment – and the onset of adverse effects. Testosterone suspensions should always be injected in the buttock muscles and not simply underneath the skin. The injection site should be rotated to prevent abscess formation. Another option is to inject the drug on the outside of the thigh. The drug should never be administered intravenously.

The dose of testosterone suspensions should not exceed more than 100-400 mg per month because of the onset of side effects. The drug should always be inspected before injection. It is usually a colorless-yellow suspension which is clear. Any particulate matter or clumping indicates that the product is expired or inactive. The duration of treatment varies from 1-2 months.

The drug should be stored at room temperature.

Bodybuilders
A lot of bodybuilders use testosterone suspensions during the off season. The drug stays in the body for a long time and it is advisable not to use it during the active sports season. The testosterone definitely has anabolic and androgenic properties. However, the effects of the drug are not immediate and may take at least 3-4 weeks to become evident. Many bodybuilders also use other anabolic hormones like GH/thyroxin in combination. Because testosterone is also converted to estrogen in the fatty tissues, many bodybuilders develop breast enlargement and retain water. The dose used to increase muscle mass and strength is about 25- 400 mg/week. However, at the higher doses the drug has potent side effects and it is highly recommended that all beginners start off with the low dose.

The increase in protein mass is gradual but does occur. Because the steroid also stimulates red blood cell production, many bodybuilders also notice that they have an increased capacity to perform under intense exercise conditions.

Testosterone suspensions are preferred by most bodybuilders but the type of formulation available depends on where and from whom it is bought. The drug has been claimed to promote good health, increase exercise performance and leads to a positive nitrogen balance. There are reports that it also selectively decreases fat and increases muscle mass. Sometimes the water retention can be quite dramatic and some individuals do take a diuretic pill to remove it.

To prevent the breast enlargement, testosterone is cycled with drugs like Arimidex orTamoxifen. Most individuals take the testosterone for 4-6 weeks and then stop for a few weeks. During this wash out phase, one may use Arimidex.

Side effects

  • irregular menstrual cycles
  • virilizing effects
  • deepening voice
  • clitoral enlargement
  • gynecomastia
  • painful penile erections
  • hair loss, acne, oily skin
  • retention of body water
  • nausea, vomiting, jaundice
  • liver cancer (rare)
  • mental changes – anger, depression, headaches, and anxiety
  • increased serum cholesterol

While most of these side effects are reversible, the breast enlargement and some virilizing effects are not. The concomitant use of estrogens to diminish the side effects of virilization is not always helpful.

Women
All testosterone analogues have the potential to cause virilizing effects when the duration of use is prolonged. In females, these virilizing signs may be deepening of voice, excessive hair growth, irregular menstrual cycles, mood alterations and clitoral enlargement. It is recommended that at the first sign of virilizing symptoms the drug should be stopped. The reason for this is that some of the virilizing signs may not be reversible even after discontinuation of the steroid.

Warnings
The drug should be used very cautiously in individuals with:

  • breast cancer and hypercalcemia
  • liver dysfunction
  • heart problems

There have been isolated reports of individuals developing a dry cough, breathing difficulties after injection with testosterone suspension. This has been linked to the oil based preparation or a contaminant in the formulation.

All individuals who use testosterone should have their liver enzymes and blood hematocrit regularly checked to ensure that they are within normal limits.

Overdose
It is very rare for anyone to overdose form tesamone. While a large dose can be injected, the drug does not have any acute effects which are life threatening. Of course, one will feel like crap for the next few weeks until the drug disappears from the body. Nevertheless, a visit to the ER is high recommended.

All individuals who do use any type of anabolic steroid should follow up with a health care worker. The liver enzymes and the hematocrit must be followed to ensure that everything is within normal limits

Legal
Testosterone is classified as a class 3 drug under the controlled substance act. The drug is only available with a physician’s prescription. However, most physicians are hesitant in writing scripts for any steroids.

Detection
Testosterone suspensions do remain in the body for some time. Current techniques of testing can identify testosterone or its metabolites in the urine at least 3-4 weeks after the drug has been stopped. Infact, the screening has even gone beyond urine testing. If excessive use of the testosterone is suspected, one can even detect traces of the testosterone in the hair 2-4 months after the drug has been stopped.

However, one should know that the testing today for testosterone suspensions is not perfect. About 50% of individuals who take this steroid are missed based on the testosterone/epitestosterone ratios.

Cost
The legal testosterone suspensions are quite difficult to get hold off. The majority of bodybuilders get their testosterone from the black market. Generic testosterone formulations made in Europe and Mexico are widely available. The drug is not cheap and a vial of 250 mg can cost anywhere from $10-$40. In the last 2 decades, the increasing control of these drugs by the DEA has led to unscrupulous dealers selling fake or counterfeit products. So in the end, it is always buyer beware.

08 Nov

Winstrol, also known as stanozolol is a synthetic anabolic steroid with many similarities to testosterone. Stanozolol is both an anabolic and androgenic hormone. In females it may have virilizing impacts. Once generally accessible and available, today it is a troublesome item to discover. In spite of the buildup on the internet about Winstrol being accessible, there have been numerous occurrences of fake definitions or contaminants in items purchased over the web.

The draw of quick income relatively easily has numerous individuals in the business of offering fake anabolic steroids on the internet. What’s more, the DEA nearly screens every site in light of the fact that the offering and conveyance of any anabolic steroid is illicit. Numerous Winstrol items sold over the web have been investigated and found to contain innocuous cholesterol like particles with contaminants. So for the bodybuilder interested in anabolic steroids, the internet is not is not the place to buy the drug as the purity cannot be established.

Indications
Winstrol a synthetic derivative of testosterone. It was first made by Winthrop laboratories in the 60s and is one of the oldest anabolic steroids on the market. It is indicated for the treatment of one major disorder in clinical medicine – hereditary angioedema. It has also been tried out as a treatment for extremely resistant cases of anemias and weight loss in HIV patients. The drug was once used to be used to treat livestock for weight gain. The intramuscular formulation given once a week was widely used but is hard to find today. The reason for this has been the widespread abuse of the drug and possible side effects.

Dose in Medicine
Winstrol is used as an intramuscular formulation in the farming industry to boost weight gain in livestock. For human use, the drug is available as an oral tablet. Stanozolol is usually given at 2 mg three times a day for hereditary angioedema. Often it is continued for 1-3 months at 2 mg per day without any undue side effects. The drug is generally safe and can be taken at low doses for many months. The anabolic effects are generally seen after a period of 3-4 weeks and continue to increase over time. The drug also has some mild androgenic effects at high doses.

Side effects
Like all anabolic steroids, winstrol also has some side effects. These effects are rare and most people tolerate them without a problem. The most common side effects include:

  • jaundice
  • hepatic necrosis – common
  • liver cancers (rare)
  • testicular atrophy
  • decreased libido
  • depression, insomnia, anger, mood changes
  • nausea, vomiting, diarrhea
  • gynecomastia
  • deepening of voice in women
  • hair loss
  • hair growth in women
  • fluid retention
  • increased blood sugars
  • decrease HDL cholesterol

While most of these changes reverse after stopping the drug, some of the virilizing effects may be irreversible. For women who do take this drug, a word of warning. The drug should be stopped at the first signs of virilization because some of the masculine features may not reverse even after the drug is stopped. Winstrol has also been associated with reports of extensive liver damage which can be life threatening. Therefore, it is highly recommended that anyone using anabolic steroids regularly has their liver function regularly monitored.

Contraindications
Winstrol is not recommended in individuals with

  • male breast cancer
  • prostate cancer
  • females with breast cancer and/or hypercalcemia
  • if a female is pregnant
  • anyone with allergies to steroidal drugs

Dosing for bodybuilders
Stanozolol is widely used by bodybuilders and other athletes. It not only increases weight gain but also increases exercise performance. The drug increases weight gain gradually but does not retain the water. It selectively burns the fat while retaining the protein. In medicine, winstrol is only used an oral drug with doses of 2 -6 mg per day in total. Because the drug has potent liver toxicity, the higher doses are not used.

The injectable formulation is milky white in color with microcrystals. Fake stanozolol injectable products are common and there is no way to tell simply by looking at a product to determine if it is fake. Some bodybuilders claim that the real winstrol will reveal settled microcrystals at the base when standing – however, talcum powder can do the same. However, bodybuilders seem to use a dose at least 2-4 times higher than that. One reason for this is that the THAI formulation appears to be less potent than the product made by Pfizer. Some bodybuilders use 10 mg/day and others use 20 mg/day. The major problem with oral dosing is that a lot of absorbed winstrol goes to the liver and is broken down. The drug can also be injected IM if one can get the supplies. The dose of an IM injection is about 50mg/week, but some bodybuilders use it 2-3 times a week. The site of injection is usually the buttocks and this site must be altered every few weeks to prevent abscess and sores.

The drug is typically used 1-2 months before a sports event. The drug must be stopped at least 2- 3 weeks before to avoid detection.

The majority of people do see muscle bulk build up after 3-4 weeks. Infact, winstrol can significantly improve exercise performance for short periods of time. Many reports exist of athletes who claim that spontaneous burst in energy are common after 3-4 weeks of use. However, this effect is not seen to last for long periods.

Despite what most builders believe higher doses of stanozolol are harmful and do not result in improved results. Most experts recommend that the drug not be used for more than 4-6 weeks.

Stanozolol is frequently used for 3-4 weeks and then cycled with other drugs. The most common other drugs are Masteron, Equipose, Oxandrolone, GH and thyroxin. Some individuals add Clomid to prevent the suppression of testosterone in the wash out period. Because stanozolol can cause water retention many athletes also use water pills to rid the excess body water.

Recently, an alternative to stanozolol is furazabol; it is identical to stanozolol in all respects except that it does improve the cholesterol profile which makes it unique among all anabolic steroids. However, this beneficial effect is only seen at low doses and for a short time period. When used at high doses for a long time, all anabolic steroids lower HDL cholesterol and increase LDL cholesterol

Females
Stanozolol is also widely used by females for two major reasons- it is a potent anabolic agent and has very small androgenic activity. This results in a body which lacks the virilizing features which are so common with the use of other anabolic steroids. However, when the drug is used at high doses or for long periods, the virilizing effects do appear. The unsightly virilizing effects are often not reversible even when the drug is stopped.

Sports
Stanozolol is banned for use by all sports organizations and its use is actively screened in the urine. The drug is easily detected in the urine for up to 5-7 days after the last dose. Most bodybuilders use this drug just before a sports event because of the mistaken belief that it is not detectable after a 2 week washout period. Recent advances in detection can identify metabolites of winstrol in the urine for up to 2 months. And one note of concern – the majority of bodybuilders are found to be users of anabolic steroids not because of the intellect of the scientists but because a colleague or someone close brags about the use.

Cost and availability
There are many sites on the internet which claim to sell Winstrol. Considering that the DEA monitors all the sites, the validity of the products is in question. The most common formulation of winstrol available in the USA is from Thailand. Winstrol is also smuggled in the country from México, Russia and Europe. Further, many injectable forms of winstrol are obtained illegally from the veterinary market. Winstrol is not a cheap product. On average, each tablet costs about $2 or 200 tablets of 2 mg each can be bought for $150-$200.

Always get your pills from a reputable dealer to ensure that you are getting your money’s worth and the right product.

Legal
Stanozolol is classified under the Controlled Substance Act as a schedule 3 drug. It requires a doctor’s prescription to acquire the medication. Anybody got in the ownership, offering or conveying the medication can be subjected to financial fines and correctional facility time. The late occurrence of steroid wraths and tragic passings, has likewise prompted stricter control on remedy accessibility of this medication. Most doctors are hesitant to give this medication out inspired by a paranoid fear of misuse and the complementary impacts may risk their professions.

30 Sep

Human growth hormone is a naturally occuring substance emitted by the foremost pituitary organ. It is key for typical development and improvement. Development hormone (GH)is discharged by the pituitary organ since conception and the levels crest around late puberty. In the second decade of life, the levels of development hormone started to decrease. For over 40 years development hormone has been accessible to treat particular restorative issue. Notwithstanding, in the previous 3 decades, development hormone lunacy has hit the business sector and everybody needs to take it. The moderately aged and elderly assume GH can turn around maturing, the youthful youngsters need to fabricate their bodies and the games competitors need to perform better. Of the considerable number of medications manhandled by games competitors, Growth hormone most likely positions in the main three.

What Human Growth Hormone?

Human growth hormone, abbreviated as HGH, hGH and GH, is the hormone that activates cell production, growth, and metabolic processes within the human body. Secreted by the anterior pituitary located just inside the base of the skull, GH is responsible for working in conjunction with other hormones in the body to stimulate and regulate proper human growth and development. GH levels generally reach their all time high at puberty and significantly decline around the age of 40. Growth hormone is readily available from many health food stores and spas. It is also widely available from many nutrient and alternative care practitioners. The growth hormones is frequently sold under other names like Genotropin®, Humatrope®, Norditropin®, Nutropin®, Saizen®, Serostim®)

Pharmacology
Most of the GH available is manufactured using recombinant DNA technology; the two types of synthetic HGH available are somatropin and somatrem. Both synthetic types have similar pharmacological actions. The synthetic forms once injected are impossible to distinguish from the naturally occurring GH. Growth hormone acts by binding to GH receptors on various tissues and stimulate a variety of cellular actions. GH has multiple physiological effects including regulation of metabolism, maintaining fluid and electrolyte balances, increasing skeletal and muscle mass. GH levels are generally increased during stress, sleep and exercise.
In which conditions do GH levels change?
There are a few medical conditions that can develop if levels of GH are either too low or too high. With an excess amount of human growth hormone the body may over produce cells causing acromegaly, a condition characterized by oversized extremities, rapid and continual cell growth, and a variety of other serious health complications; or pituitary gigantism, which results in extreme height due to over secretion of GH. Medical conditions caused by GH deficiency can be serious as well, leading to a variety of short stature conditions that may severely impact overall health. Approved clinical uses of GH
The FDA has several approved injectable preparations of HGH. The growth hormone is only available with a prescription from a licensed physician. Synthetically derived (recombinant) GH was initially approved by the FDA in 1985 for the treatment of short stature due to GH deficiency (GHD). In the following years, GH continued to gain approval for the treatment of specific clinical conditions causing short stature and other complications related to lifelong GHD such as Prader-Willi syndrome, short stature caused by chronic renal insufficiency, Turner syndrome, idiopathic short stature, and intrauterine growth retardation. The FDA has also approved GH therapy as a treatment for growth hormone deficiency attributed to the presence of pituitary tumors. Another recent approved use for GH has been to treat adults who develop the wasting syndrome of AIDS.
There is a lot of evidence that shows that injection of GH in the above mentioned disorders can result in:
increased muscle mass and bone density
decreased body fat
improved mentation
increased exercise performance
increased cardiovascular tolerance to stress/exercise

Dosing
GH is never taken orally. It is always administered as an injection- either subcutaneous or intramuscular. GH acts pretty rapidly once it is absorbed in the blood stream. The dosing of growth hormone is still not fully known. While the latest research indicates it should be based on levels of IGF, many physicians dose it based on body weight. For adults, the dosing is about 0.01-0.1 mg/kg body weight. This dosing depends on the type of product and what it is to be used for. The currently available GH either comes as a powder or a liquid. The powder is solubilized in a saline solution before injection.
Side effects of growth hormone
GH can cause several side effects, which are disturbing. The most common include:
Generalized edema
Carpal tunnel syndrome
Joint and muscle pain
Neuropathies (e.g., numbness and tingling)
Increase blood glucose levels

Does one require a prescription for GH?
GH can only be legally prescribed for the aforementioned purposes approved by the FDA; however, many off-label uses for the hormone exist, such as athletic performance enhancement and anti-aging treatment. In most instances of off-label usage, the FDA has not approved GH treatment simply because the potential benefits of therapy do not outweigh the possible risks posed by altering the body’s levels of GH. While touted by some as a miracle cure-all, GH carries with it serious side effects that patients should take heed of before initiating treatment.
Potential risks of taking GH
With GH there is the ever-present risk of overdose, which can lead to the development of devastating conditions brought on by excessive GH production, such as acromegaly. Since GH stimulates cell growth, there is also the risk that GH may activate the proliferation of unwanted cells like cancer cells, causing the development of leukemia, prostate cancer, and malignant tumors in those undergoing GH therapy. Comparatively less serious side effects of GH include fluid retention, carpal tunnel syndrome, joint pain, and type 2 diabetes. Anti-agers considering GH therapy must carefully weigh the risks and benefits of treatment before deciding to follow through with the potentially harmful therapy.
Off Label Use
bodybuilding
The major off label uses of GH are for anti aging and for bodybuilding. GH is one of the most widely abused drugs by sports athletes. The drug is widely available but is illegal to possess or sell. The majority of bodybuilder use a whole cocktail of drugs together with HGH. Which drug actually leads to better a body is difficult to know because these individuals do take so many drugs. Another reason why GH is widely abused by many athletes is because the drug is somewhat difficult to detect.
The exact number of individuals who take GH remains unknown but every now and then an occasional athlete will confess to abusing it.
For the bodybuilder, GH does not come cheap. Depending on where one buys from and from whom, the monthly costs can run anywhere from $500-$2000. And in some cases, the GH is fake.
Anti Aging
Another off label use of GH is in the quest for remaining youthful. Many people want to reverse the lines and wrinkles on their face and have turned to growth hormone. Despite all the hype about GH, it is not approved for anti aging treatment. And there is no evidence that it can reverse any lines, wrinkles or change skin texture.
Because of the much advertised success and popularity of human growth hormone, ineffective “copy cat” treatments sold mainly in pill form are purported to generate a $70 million industry. Anti-aging “suckers” will pay between ten and twenty thousand dollars a year for real GH injections, most commonly administered in an anti-aging clinic or medical spa setting.
Availability
The majority of individuals get their HGH through illegal means. In some cases, the product is stolen from pharmacies. Sometimes it is unscrupulous physicians who prescribe it for off label use. GH is also smuggled in from Mexico and Europe. There are also many pharmacies in cyberspace that sell GH. In the majority of cases, the internet pharmacies are run by physicians who simply write a prescription without seeing the patient. Many individuals buy GH this way and then sell it on the black market.
Even though the only appropriate way to administer HG is via an injection, there are many people who market GH as a spray pill or a topical gel. The GH molecule is only minimally absorbed when inhaled or placed underneath the tongue.
Limitations of testing
Synthetic GH is very difficult to detect in the body. The current methods can’t detect GH more than 48 hours after the last injection and most athletes are aware of this fact. A favorite question by any athlete today before he starts to take any illicit drug is if there is a test for it.
Sermorelin
Sermorelin is a relatively new drug which has been counterfeited in China from the original drug, Geref. Sermorelin is a biological active analog of growth hormone releasing hormone (GHRH) that is produced by the human hypothalamus to stimulate production and release of growth hormone by the anterior pituitary gland. Sermorelin is neither detected in the blood or urine after a certain time period. So for the moment, things are status quo with the sports organizations and only the dumbest athlete is ever caught with GH.
Sermorelin when administered takes at least 3-4 weeks to work before the effects are obvious. It gradually builds up strength and has none of the major side effects of Growth hormone. Sermorelin is generally designed to treat the aging population and is not an effective replacement for GH. If your body has no GH, then Sermorelin will do very little for you. Sermorelin costs anywhere from $300-$1000 for a month’s supply.
Control Status
The widespread abuse of HG has led to some Federal Regulations limiting it sells and distribution. The 1990 Anabolic Steroids Control Act now means that anyone possessing, selling, distribution GH is committing a crime. There are serious penalties for such acts and include jail time and monetary fines. In March 2007, a bill was introduced into the U.S. Senate to amend the Controlled Substances Act and add HGH to schedule III. GH is currently listed by the World Anti-Doping Agency and the International Olympic Committee as a performance enhancing drug barring athletes from using it.