Testosterone Enanthate (delatestryl)
Testosterone is in charge of the typical development and advancement of the male sex organs and for the upkeep of the optional sexual qualities. The medication can influence the development of the prostate, testis, fundamental vesicles, penis and scrotum furthermore is essential for body development. Despite the fact that testosterone is an androgenic hormone, it does gangs anabolic properties. Its utilization has been appeared to advance protein combination and a positive nitrogen equalization in the vicinity of a rich calorie diet.
Testosterone likewise can bring about a mellow increment in the creation of red platelets by invigorating the amalgamation of from the kidney. This outcomes in an expansion in the red platelets and thus an expansion in the oxygen conveying limit.
At the point when testosterone is taken for delayed periods, it represses the arrival of Gonadotropins from the pituitary organ through a negative criticism system. Everywhere dosages, it can even hinder spermatogenesis.
Testosterone likewise can bring about a gentle increment in the creation of red platelets by animating the union of EPO from the kidney. This outcomes in an expansion in the red platelets and thus an increment in the oxygen conveying limit.
At the point when testosterone is taken for delayed periods, it hinders the arrival of Gonadotropins from the pituitary organ through a negative criticism system. Everywhere measurements, it can even repress spermatogenesis.
Testosterone enanthate (Delatestryl) is only slowly released after an intramuscular injection and that is why it should not be taken more than 1-2 times a month. The formulation comes as an esterified preparation of testosterone which is only meant to be administered by an intramuscular injection. The esterification of the testosterone increases the duration of action of the testosterone. The preparation comes in a colorless to mild yellow suspension of sesame oil. For medical uses, a dose of 250-500mg is used once a month.
Delatestryl is indicated in the treatment of conditions where testosterone is either deficient or absent. These conditions include:
- primary hypogonadism- where the testes has been injured and fails to make the testosterone
- Hypogonadism due to failure of the pituitary gland to release of Gonadotropins.
- delayed puberty
- In females with breast cancer, testosterone may help block the effects of estrogen and prevent further spread. It is an option instead of surgical removal of the ovaries.
In most cases of testosterone deficiency, therapy is required for a long time until the secondary sexual characteristic have been developed and the growth is adequate.
The treatment of all people with testosterone enanthate relies on upon age, sex, finding and the reaction to treatment-and the onset of unfavorable impacts. By and large, the medication is all around endured when endorsed as suggested. Delatestryl ought to dependably be infused in the butt cheek muscles and not just underneath the skin. The infusion site ought to be turned to forestall ulcer development. Another choice is to infuse the medication on the outside of the thigh. The medication ought to never be regulated intravenously.
The measurement of testosterone enanthate ought not surpass more than 400 mg for every month on the grounds that the medication has drawn out action. It is to a great degree uncommon to give this medication once like clockwork. The medication ought to dependably be examined before infusion. It is normally a dry yellow suspension which is clear. Any particulate matter or clustering shows that the item is terminated or dormant. The term of treatment changes from 4-6 months.
The drug should be stored at room temperature.
A lot of bodybuilders use Delatestryl during the off season. The drug stays in the body for a long time and it is advisable not to use it during the active sports season. The drug definitely has anabolic and androgenic properties. However, the effects of the drug are not immediate and may take at least 3-4 weeks to become evident. Many bodybuilders also use other anabolic hormones like GH/thyroxin in combination.
Because testosterone is also converted to estrogen in the fatty tissues, many bodybuilders develop breast enlargement and retain water. The dose used to increase muscle mass and strength is about 250-1000 mg/week. However, at the higher doses the drug has potent side effects and it is highly recommended that all beginners start off with the low dose.
The increase in protein mass is gradual but does occur. Because the steroid also stimulates red blood cell production, many bodybuilders also notice that they have an increased capacity to perform under intense exercise conditions. Testosterone enanthate is preferred by most bodybuilders because it is readily available and has a number of benefits. It promotes good health, increase exercise performance and leads to a positive nitrogen balance. There are reports that it also selectively decreases fat and increases muscle mass. Recent studies from the World sports agencies indicate that this particular drug can boost performance, increase lean muscle mass and still not bedetected in the urine within the first few weeks. Even when the anabolic effects are not obvious, most individuals do notice an increase in strength. Sometimes the water retention can be quite dramatic and some individuals do take a diuretic pill to remove it. To prevent the breast enlargement, testosterone enanthate is cycled with drugs like Arimidex or Tamoxifen. Most individuals take the testosterone for 4-6 weeks and then stop for a few weeks. During this wash out phase, one may use Arimidex.
All testosterone analogues have the potential to cause virilizing effects when the duration of use is prolonged. In females, these virilizing signs may be deepening of voice, excessive hair growth, irregular menstrual cycles, mood alterations and clitoral enlargement. It is recommended that at the first sign of virilizing symptoms the drug should be stopped. The reason for this is that some of the virilizing signs may not be reversible even after discontinuation of the steroid.
Like all anabolic steroids, testosterone enanthate has a few side effects. These side effects are generally mild and well tolerated. The majority of individuals do see some side effects after 3-4 months of therapy. The most common side effects include:
- irregular menstrual cycles
- virilizing effects
- deepening voice
- clitoral enlargement
- painful penile erections
- hair loss, acne oily skin
- retention of body water
- nausea, vomiting, jaundice
- liver cancer (rare)
- mental changes, depression, headaches, anxiety,
- increased serum cholesterol
While most of these side effects are reversible, the breast enlargement and some virilizing effects are not. The concomitant use of estrogens to diminish the side effects of virilization is not always helpful.
In children the use of testosterone must be strictly monitored. It can accelerate bone maturation but does not increase compensatory linear growth – which results in abnormal body distortion in anatomy- esp. the jaw and face.
The drug should be used very cautiously in individuals with:
- breast cancer and hypercalcemia
- liver dysfunction
- prostate cancer
- heart problems
There have been isolated reports of individuals developing a dry cough, breathing difficulties after injection with testosterone enanthate. This has been linked to the oil based preparation or a contaminant in the formulation.
All individuals who use testosterone should have their liver enzymes and blood hematocrit regularly checked to ensure that they are within normal limits.
Delatestryl is classified as a class 3 drug under the controlled substance act. In the USA, it is only available with a physician’s prescription.
Testosterone enanthate has a long half life in the body. Consequently it is additionally identified in the pee long after it has been stopped. Current methods of testing can recognize testosterone or its metabolites in the pee no less than 3-4 weeks after the medication has been ceased. Infact, the testing has even gone past pee testing. In the event that exorbitant utilization of the testosterone is suspected, one can even detect hints of the testosterone in the hair 2-4 months after the medication has been abated.
However, one should know that the testing today for testosterone enanthate is not perfect. About 50% of individuals who take this steroid are missed based on the testosterone/epitestosterone ratios.
The legal testosterone enanthate is quite difficult to get hold off. The majority of bodybuilders get their testosterone from the black market. Generic testosterone formulations made in Europe and Mexico are widely available. The drug is not cheap and a vial of 250 mg can cost anywhere from $10-$20. In the last 2 decades, the increasing control of these drugs by the DEA has led to unscrupulous dealers selling fake or counterfeit products. So in the end, it is always buyer beware.